ABOUT PROSpect

The PRone and OScillation Pediatric Clinical Trial (PROSpect) is an international clinical research study funded by the National Institutes of Health (NIH) Heart, Lung and Blood Division (NHLBI), which is now closed to enrollment and the primary publication can be found here.

Briefly, when children’s lungs are very sick they often need a machine to help them breathe (ventilator).  There are different types of breathing machines; conventional or high frequency. Children can also be placed in different positions while on a breathing machine.  The child could lie on their back (supine position) or lie on their stomach (prone position). The goal of PROSpect was to learn the best way to use breathing machines and positioning when children with very sick lungs are unable to breathe for themselves. For further information please see clinicaltrials.gov